TORC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86925

Novus Biologicals, part of Bio-Techne
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NBP1-86925
NBP1-86925-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TORC2 Antibodies »

Product Summary for TORC2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGIN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TORC2 Antibody

Western Blot: TORC2 Antibody [NBP1-86925]

Western Blot: TORC2 Antibody [NBP1-86925]

Western Blot: TORC2 Antibody [NBP1-86925] - Analysis in control (vector only transfected HEK293T lysate) and CRTC2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: TORC2 Antibody [NBP1-86925]

Immunocytochemistry/ Immunofluorescence: TORC2 Antibody [NBP1-86925]

Immunocytochemistry/Immunofluorescence: TORC2 Antibody [NBP1-86925] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: TORC2 Antibody [NBP1-86925]

Immunohistochemistry-Paraffin: TORC2 Antibody [NBP1-86925]

Immunohistochemistry-Paraffin: TORC2 Antibody [NBP1-86925] - Staining of human cerebral cortex shows strong nuclear positivity in neurons and glial cells.

Applications for TORC2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TORC2

TORC2 (transducer of regulated CREB activity 2) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC1 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. TORC2 has been found to be pivotal to the process of gluconeogenesis. TORC2 is also known as CREB regulated transcription activator 2, and CRTC2.

Long Name

Transducer of Regulated CREB protein 1

Alternate Names

CRTC2

Gene Symbol

CRTC2

Additional TORC2 Products

Product Documents for TORC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TORC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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