TP53INP2 Antibody [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-71704G

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TP53INP2 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to a C-terminal region of the human TP53INP2 protein (within residues 100-220). [Swiss-Prot Q8IXH6]

Reactivity Notes

Immunogen has 81% identity to rat.

Localization

Nucleus.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for TP53INP2 Antibody [DyLight 488]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TP53INP2

Tumor protein p53 inducible nuclear protein 2 is necessary for tumor cell invasive migration. Different splicing events in formation of this protein are key determinants of whether the tumor cell invasive morphology exists, and is probably mediated through a Golgi complex interaction. TP53INP2 also binds the Atg8-like proteins and VMP1 during autophagy, and generates scaffolding for autophagosome membranes. LC3 and LC3R also interact with TP53INP2 through an interaction with the autophagosome transmembrane protein VMP1. Thus, the effect of TP53INP2 on tumor growth seems to be both a direct effect on invasion and an indirect effect of insufficient autophagosome scaffolding and inflammation events in response to tumor formation.

Alternate Names

C20orf110, chromosome 20 open reading frame 110, diabetes and obesity regulated, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, p53-inducible protein U, PINHPIG-U, tumor protein p53 inducible nuclear protein 2, tumor protein p53-inducible nuclear protein 2

Gene Symbol

TP53INP2

Additional TP53INP2 Products

Product Documents for TP53INP2 Antibody [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TP53INP2 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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