Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Porcine (100%), Rabbit (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TPT1/TCTP Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the center of human TPT1. The immunogen is located within amino acids 80 - 130 of TPT1. Amino Acid Squence: DYMKSIKGKLEEQRPERVK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TPT1/TCTP Antibody - BSA Free

Western Blot: TPT1/TCTP AntibodyBSA Free [NBP2-41206]

Western Blot: TPT1/TCTP AntibodyBSA Free [NBP2-41206]

Western Blot: TPT1/TCTP Antibody [NBP2-41206] - Western blot analysis of TPT1 in human brain tissue lysate with TPT1 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunohistochemistry: TPT1/TCTP Antibody - BSA Free [NBP2-41206]

Immunohistochemistry: TPT1/TCTP Antibody - BSA Free [NBP2-41206]

Immunohistochemistry: TPT1/TCTP Antibody [NBP2-41206] - TPT1 in rat brain tissue with TPT1 antibody at 20 ug/ml.
Immunohistochemistry: TPT1/TCTP Antibody - BSA Free [NBP2-41206]

Immunohistochemistry: TPT1/TCTP Antibody - BSA Free [NBP2-41206]

Immunohistochemistry: TPT1/TCTP Antibody [NBP2-41206] - Immunohistochemistry of TPT1 in rat brain tissue with TPT1 antibody at 2.5 ug/ml.
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Applications for TPT1/TCTP Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TPT1/TCTP

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.

Long Name

Translationally-controlled Tumor Protein 1

Alternate Names

Fortilin, HRF, p02, TCTP

Gene Symbol

TPT1

Additional TPT1/TCTP Products

Product Documents for TPT1/TCTP Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TPT1/TCTP Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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