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TRACP/PAP/ACP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38874

Novus Biologicals, part of Bio-Techne
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NBP2-38874
NBP2-38874-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for TRACP/PAP/ACP5 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: THCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRACP/PAP/ACP5 Antibody

Immunohistochemistry-Paraffin: TRACP/PAP/ACP5 Antibody [NBP2-38874]

Immunohistochemistry-Paraffin: TRACP/PAP/ACP5 Antibody [NBP2-38874]

Immunohistochemistry-Paraffin: TRACP/PAP/ACP5 Antibody [NBP2-38874] - Staining of human lung shows strong cytoplasmic positivity in macrophages.

Applications for TRACP/PAP/ACP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRACP/PAP/ACP5

TRACP is an iron-containing, 35 kDa glycoprotein that hydrolyses phosphomonoesters. It is produced as a monomer by osteoclasts and is cleaved by cathepsins to create a disulfide-linked dimer that acts on bone matrix phosphoserine-containing proteins in lysosomal vesicles. Following phosphate cleavage, TRACP is released from the cell where it serves as a marker of bone resorption.

Long Name

Tartrate Resistant Acid Phosphatase 5

Alternate Names

ACP5, TRACP-5b, TTRRAP

Gene Symbol

ACP5

UniProt

Additional TRACP/PAP/ACP5 Products

Product Documents for TRACP/PAP/ACP5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TRACP/PAP/ACP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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