TRAF-2 Antibody [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77248CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-77248AF350

Alexa Fluor 405

NBP1-77248AF405

Alexa Fluor 488

NBP1-77248AF488

Alexa Fluor 532

NBP1-77248AF532

Alexa Fluor 594

NBP1-77248AF594

Alexa Fluor 647

NBP1-77248AF647

Alexa Fluor 700

NBP1-77248AF700

Alexa Fluor 750

NBP1-77248AF750

Biotin

NBP1-77248B

DyLight 350

NBP1-77248UV

DyLight 405

NBP1-77248V

DyLight 488

NBP1-77248G

DyLight 550

NBP1-77248R

DyLight 594

NBP1-77248DL594

DyLight 650

NBP1-77248C

DyLight 680

NBP1-77248FR

DyLight 755

NBP1-77248IR

FITC

NBP1-77248F

HRP

NBP1-77248H

Janelia Fluor 525

NBP1-77248JF525

Janelia Fluor 549

NBP1-77248JF549

Janelia Fluor 585

NBP1-77248JF585

Janelia Fluor 635

NBP1-77248JF635

Janelia Fluor 646

NBP1-77248JF646

Janelia Fluor 669

NBP1-77248JF669

mFluor Violet 450 SE

NBP1-77248MFV450

mFluor Violet 500 SE

NBP1-77248MFV500

mFluor Violet 610 SE

NBP1-77248MFV610

PerCP

NBP1-77248PCP

Forumulation

Catalog #

BSA Free

NBP1-77248

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAF-2 Antibodies »

Product Summary for TRAF-2 Antibody [CoraFluor™ 1]

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human TRAF2. The immunogen is located within amino acids 180 - 230 of TRAF2. Amino Acid Squence: CGKKKIPREKFQDHVK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for TRAF-2 Antibody [CoraFluor™ 1]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: TRAF-2

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. TRAF2 is typically described as a 501 amino acid (aa) protein, GenBank no. NP_066961.2. However, various TRAF2 isoforms have been described. Therefore the molecular weight of TRAF2 detected by Western blot may vary depending on isoforms expressed.

Long Name

TNF Receptor-Associated Factor 2

Alternate Names

TRAF2, TRAP3

Gene Symbol

TRAF2

Additional TRAF-2 Products

Product Documents for TRAF-2 Antibody [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRAF-2 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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