TRAILR1/TNFRSF10A Antibody (B-N36) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14599

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Alexa Fluor 350

NBP3-14599AF350

Alexa Fluor 405

NBP3-14599AF405

Alexa Fluor 488

NBP3-14599AF488

Alexa Fluor 532

NBP3-14599AF532

Alexa Fluor 594

NBP3-14599AF594

Alexa Fluor 647

NBP3-14599AF647

Alexa Fluor 700

NBP3-14599AF700

Alexa Fluor 750

NBP3-14599AF750

Allophycocyanin

NBP3-14599APC

Biotin

NBP3-14599B

CoraFluor 1

NBP3-14599CL1

DyLight 350

NBP3-14599UV

DyLight 405

NBP3-14599V

DyLight 488

NBP3-14599G

DyLight 550

NBP3-14599R

DyLight 594

NBP3-14599DL594

DyLight 650

NBP3-14599C

DyLight 680

NBP3-14599FR

DyLight 755

NBP3-14599IR

FITC

NBP3-14599F

HRP

NBP3-14599H

Janelia Fluor 525

NBP3-14599JF525

Janelia Fluor 549

NBP3-14599JF549

Janelia Fluor 585

NBP3-14599JF585

Janelia Fluor 635

NBP3-14599JF635

Janelia Fluor 646

NBP3-14599JF646

Janelia Fluor 669

NBP3-14599JF669

mFluor Violet 450 SE

NBP3-14599MFV450

mFluor Violet 500 SE

NBP3-14599MFV500

mFluor Violet 610 SE

NBP3-14599MFV610

PE

NBP3-14599PE

PerCP

NBP3-14599PCP

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # B-N36

Format

Azide and BSA Free

Concentration

1 mg/ml

View all TRAILR1/TNFRSF10A Antibodies »

Product Summary for TRAILR1/TNFRSF10A Antibody (B-N36) - Azide and BSA Free

Immunogen

Recombinant human TRAILR1/TNFRSF10A

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Applications for TRAILR1/TNFRSF10A Antibody (B-N36) - Azide and BSA Free

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Biological Activity: Neutralizes TRAIL induced apoptosis on HEL cell line

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAILR1/TNFRSF10A

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Long Name

TRAIL Receptor 1

Alternate Names

CD261, DR4, TNFRSF10A, TRAIL R1

Gene Symbol

TNFRSF10A

Additional TRAILR1/TNFRSF10A Products

Product Documents for TRAILR1/TNFRSF10A Antibody (B-N36) - Azide and BSA Free

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRAILR1/TNFRSF10A Antibody (B-N36) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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