TRAILR2/TNFRSF10B Antibody (TR2.21) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80070B

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-80070AF350

Alexa Fluor 405

NBP2-80070AF405

Alexa Fluor 488

NBP2-80070AF488

Alexa Fluor 532

NBP2-80070AF532

Alexa Fluor 594

NBP2-80070AF594

Alexa Fluor 647

NBP2-80070AF647

Alexa Fluor 700

NBP2-80070AF700

Alexa Fluor 750

NBP2-80070AF750

Allophycocyanin

NBP2-80070APC

CoraFluor 1

NBP2-80070CL1

DyLight 350

NBP2-80070UV

DyLight 405

NBP2-80070V

DyLight 488

NBP2-80070G

DyLight 550

NBP2-80070R

DyLight 594

NBP2-80070DL594

DyLight 650

NBP2-80070C

DyLight 680

NBP2-80070FR

DyLight 755

NBP2-80070IR

FITC

NBP2-80070F

HRP

NBP2-80070H

Janelia Fluor 525

NBP2-80070JF525

Janelia Fluor 549

NBP2-80070JF549

Janelia Fluor 585

NBP2-80070JF585

Janelia Fluor 635

NBP2-80070JF635

Janelia Fluor 646

NBP2-80070JF646

Janelia Fluor 669

NBP2-80070JF669

mFluor Violet 450 SE

NBP2-80070MFV450

mFluor Violet 500 SE

NBP2-80070MFV500

mFluor Violet 610 SE

NBP2-80070MFV610

PE

NBP2-80070PE

PerCP

NBP2-80070PCP

Forumulation

Catalog #

BSA Free

NBP2-80070

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ Clone # TR2.21

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAIL R2/TNFRSF10B Antibodies »

Product Specifications

Immunogen

Recombinant human TRAILR2/TNFRSF10B (DR5).

Specificity

Recognizes human TRAILR2/TNFRSF10B. Does not cross-react with human TRAIL-R1, -R3 or -R4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for TRAILR2/TNFRSF10B Antibody (TR2.21) [Biotin]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRAIL R2/TNFRSF10B

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently (1-2). Like DR4, DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. DR5 binds to TRAIL and mediates TRAIL induced cell death. Overexpression of DR5 induces apoptosis and activates NF-kB.

Long Name

TRAIL Receptor 2

Alternate Names

CD262, DR5, TNFRSF10B, TRAILR2

Gene Symbol

TNFRSF10B

Additional TRAIL R2/TNFRSF10B Products

Product Documents for TRAILR2/TNFRSF10B Antibody (TR2.21) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRAILR2/TNFRSF10B Antibody (TR2.21) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews