TRAILR3/TNFRSF10C Antibody (TR3.06) [Janelia Fluor® 585]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80071JF585

Novus Biologicals, part of Bio-Techne
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NBP2-80071JF585
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NBP2-80071
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Janelia Fluor 585

Antibody Source

Monoclonal Mouse IgG1 Clone # TR3.06

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRAIL R3/TNFRSF10C Antibodies »

Product Summary for TRAILR3/TNFRSF10C Antibody (TR3.06) [Janelia Fluor® 585]

Immunogen

Recombinant human TRAILR3/TNFRSF10C (DcR1).

Specificity

Recognizes human TRAILR3/TNFRSF10C. Does not cross-react with human TRAIL-R1, -R2 or -R4.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TRAILR3/TNFRSF10C Antibody (TR3.06) [Janelia Fluor® 585]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRAIL R3/TNFRSF10C

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.

Long Name

TRAIL Receptor 3

Alternate Names

CD263, DcR1, TNFRSF10C, TRAILR3

Gene Symbol

TNFRSF10C

Additional TRAIL R3/TNFRSF10C Products

Product Documents for TRAILR3/TNFRSF10C Antibody (TR3.06) [Janelia Fluor® 585]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRAILR3/TNFRSF10C Antibody (TR3.06) [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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