TRAILR3/TNFRSF10C Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76881

Novus Biologicals, part of Bio-Techne
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NBP1-76881
NBP1-76881SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TRAIL R3/TNFRSF10C Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids in a extracellular domain of human DcR1 precursor. The immunogen is located within amino acids 140 - 190 of DcR1. Amino Acid Squence: CVEEFGANATVETPAAEET

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TRAILR3/TNFRSF10C Antibody - BSA Free

Western Blot: TRAILR3/TNFRSF10C AntibodyBSA Free [NBP1-76881]

Western Blot: TRAILR3/TNFRSF10C AntibodyBSA Free [NBP1-76881]

Western Blot: TRAILR3/TNFRSF10C Antibody [NBP1-76881] - Analysis of 20 ug of whole cell lysate from HeLa (Lane 1) and 293 (Lane 2) cells with anti-TRAIL-R3 at 1 ug/ml dilution. Image submitted by a verified customer review.
Immunocytochemistry/ Immunofluorescence: TRAILR3/TNFRSF10C Antibody - BSA Free [NBP1-76881]

Immunocytochemistry/ Immunofluorescence: TRAILR3/TNFRSF10C Antibody - BSA Free [NBP1-76881]

Immunocytochemistry/Immunofluorescence: TRAILR3/TNFRSF10C Antibody [NBP1-76881] - HeLa cells with DcR1 antibody at 10 ug/mL.
Western Blot: TRAILR3/TNFRSF10C AntibodyBSA Free [NBP1-76881]

Western Blot: TRAILR3/TNFRSF10C AntibodyBSA Free [NBP1-76881]

Western Blot: TRAILR3/TNFRSF10C Antibody [NBP1-76881] - HeLa whole cell lysate with TRAIL-R3 antibody (ED) at 1:500 dilution.
View 1 more images

Applications for TRAILR3/TNFRSF10C Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/ml

Western Blot

0.5 ug/ml
Application Notes
An approximate 65 kDa band can be detected in Western Blot. TRAILR3/TNFRSF10C antibody validated for WB from a verified customer review.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TRAIL R3/TNFRSF10C

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL. Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD. DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain. It is a glycophospholipid-anchored cell surface protein. DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines. Overexpression of DcR1 did not induce apoptosis, but attenuated TRAIL-induced apoptosis.

Long Name

TRAIL Receptor 3

Alternate Names

CD263, DcR1, TNFRSF10C, TRAILR3

Gene Symbol

TNFRSF10C

UniProt

AF012536 (Human)

Additional TRAIL R3/TNFRSF10C Products

Product Documents for TRAILR3/TNFRSF10C Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TRAILR3/TNFRSF10C Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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