Transglutaminase 1/TGM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00007051-B02P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Transglutaminase 1/TGM1 Antibodies »

Product Specifications

Immunogen

TGM1 (AAH34699, 1 a.a. - 817 a.a.) full-length human protein. MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGRSFWARCCGCCSCRNAADDDWGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA

Specificity

TGM1 - transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase),

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Transglutaminase 1/TGM1 Antibody

Western Blot: Transglutaminase 1/TGM1 Antibody [H00007051-B02P]

Western Blot: Transglutaminase 1/TGM1 Antibody [H00007051-B02P]

Western Blot: Transglutaminase 1/TGM1 Antibody [H00007051-B02P] - Analysis of TGM1 expression in transfected 293T cell line by TGM1 polyclonal antibody. Lane 1: TGM1 transfected lysate(89.87 KDa). Lane 2: Non-transfected lysate.
Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [H00007051-B02P]

Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [H00007051-B02P]

Immunohistochemistry-Paraffin: Transglutaminase 1/TGM1 Antibody [H00007051-B02P] - Analysis of purified antibody to TGM1 on formalin-fixed paraffin-embedded human uterine cervix. (antibody concentration 3 ug/ml)

Applications for Transglutaminase 1/TGM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control. It has been used for IHC-P.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Transglutaminase 1/TGM1

The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq]

Alternate Names

ICR2, KTG, LI1, TGase-1, TGK, TGM1

Entrez Gene IDs

7051 (Human)

Gene Symbol

TGM1

UniProt

AAH34699 (Human)

Additional Transglutaminase 1/TGM1 Products

Product Documents for Transglutaminase 1/TGM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Transglutaminase 1/TGM1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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