Triosephosphate isomerase Antibody (SR1406)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22185

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22185-100ul
NBP3-22185-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1406

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Triosephosphate isomerase Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Triosephosphate isomerase (Uniprot #: P60174)

Specificity

Detects endogenous levels of total Triosephosphate isomerase

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Triosephosphate isomerase Antibody (SR1406)

Western Blot: Triosephosphate isomerase Antibody (SR1406) [NBP3-22185] -

Western Blot: Triosephosphate isomerase Antibody (SR1406) [NBP3-22185] - Western blot analysis using NBP3-22185 in HeLa cell lysate.

Applications for Triosephosphate isomerase Antibody (SR1406)

Application
Recommended Usage

Flow Cytometry

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Triosephosphate isomerase

Triosephosphate isomerase (TIM) catalyses the reversible interconversion of G3P and DHAP. Only G3P can be used in glycolysis, therefore TIM is essential for energy production, allowing two molecules of G3P to be produced for every glucose molecule, thereby doubling the energy yield. Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) . TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.

Alternate Names

EC 5.3.1.1, MGC88108, TIM, TPI, triosephosphate isomerase, Triose-phosphate isomerase, triosephosphate isomerase 1

Gene Symbol

TPI1

Additional Triosephosphate isomerase Products

Product Documents for Triosephosphate isomerase Antibody (SR1406)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Triosephosphate isomerase Antibody (SR1406)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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