Troponin I Type 1 (slow skeletal) Antibody (SR1356)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22106

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22106-100ul
NBP3-22106-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1356

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Troponin I Type 1 (slow skeletal) Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Troponin I Type 1 [slow skeletal] (Uniprot #: P19237)

Specificity

Detects endogenous levels of total Troponin I Type 1 (slow skeletal)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Troponin I Type 1 (slow skeletal) Antibody (SR1356)

Western Blot: Troponin I Type 1 (slow skeletal) Antibody (SR1356) [NBP3-22106] -

Western Blot: Troponin I Type 1 (slow skeletal) Antibody (SR1356) [NBP3-22106] - Western blot analysis using NBP3-22106 in Human fetal heart lysate.

Applications for Troponin I Type 1 (slow skeletal) Antibody (SR1356)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Troponin I Type 1 (slow skeletal)

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. (provided by RefSeq)

Alternate Names

DKFZp451O223, slow-twitch isoform, SSTNI, TNN1, troponin I type 1 (skeletal, slow), troponin I, skeletal, slow, troponin I, slow skeletal muscle

Gene Symbol

TNNI1

Additional Troponin I Type 1 (slow skeletal) Products

Product Documents for Troponin I Type 1 (slow skeletal) Antibody (SR1356)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Troponin I Type 1 (slow skeletal) Antibody (SR1356)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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