Troponin T type 1 (slow skeletal) Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00007138-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Invertebrate

Cited:

Mollusca

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Troponin T type 1 (slow skeletal) Antibodies »

Product Specifications

Immunogen

TNNT1 (NP_003274, 1 a.a. - 251 a.a.) full-length human protein. MSDTEEQEYEEEQPEEEAAEEEEEEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK

Reactivity Notes

invertebrate reactivity reported in scientific literature (PMID: 26213227).

Specificity

TNNT1 - troponin T type 1 (skeletal, slow),

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Troponin T type 1 (slow skeletal) Antibody

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P] - Human skeletal muscle lysate. Image from verified customer review.
Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P] - Analysis of TNNT1 expression in transfected 293T cell line by TNNT1 polyclonal antibody. Lane 1: TNNT1 transfected lysate(27.61 KDa). Lane 2: Non-transfected lysate.
Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [H00007138-B01P] - Analysis of TNNT1 expression in SJCRH30.

Applications for Troponin T type 1 (slow skeletal) Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Reviewed Applications

Read 1 review rated 4 using H00007138-B01P in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Troponin T type 1 (slow skeletal)

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

ANMtroponin T, slow skeletal muscle, FLJ98147, MGC104241, Slow skeletal muscle troponin T, sTnT, TNTS, TNTtroponin T1, skeletal, slow, troponin T type 1 (skeletal, slow), troponin-T1, skeletal, slow

Entrez Gene IDs

7138 (Human)

Gene Symbol

TNNT1

UniProt

NP_003274 (Human)

Additional Troponin T type 1 (slow skeletal) Products

Product Documents for Troponin T type 1 (slow skeletal) Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Troponin T type 1 (slow skeletal) Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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