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Troponin T type 1 (slow skeletal) Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32748

Novus Biologicals, part of Bio-Techne
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NBP1-32748

Key Product Details

Species Reactivity

Validated:

Human, Porcine

Predicted:

Bovine (91%), Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Full length human Troponin T type 1 (slow skeletal) (slow) skeletal muscle Recombinant protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

33 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Troponin T type 1 (slow skeletal) Antibody

Western Blot: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Western Blot: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748] - Sample (30 ug of whole cell lysate)A: H129910% SDS PAGE, antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748] - Porcine skeletal muscle, using Troponin T1 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748]

Immunohistochemistry-Paraffin: Troponin T type 1 (slow skeletal) Antibody [NBP1-32748] - Human colon carcinoma, using Troponin T1 (slow skeletal) antibody at 1:500 dilution.Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for Troponin T type 1 (slow skeletal) Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Troponin T type 1 (slow skeletal)

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Alternate Names

ANMtroponin T, slow skeletal muscle, FLJ98147, MGC104241, Slow skeletal muscle troponin T, sTnT, TNTS, TNTtroponin T1, skeletal, slow, troponin T type 1 (skeletal, slow), troponin-T1, skeletal, slow

Gene Symbol

TNNT1

Additional Troponin T type 1 (slow skeletal) Products

Product Documents for Troponin T type 1 (slow skeletal) Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Troponin T type 1 (slow skeletal) Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.