TRPC6 Antibody (TRPC6/7671) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27020PE

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-26738

Alexa Fluor 350

NBP3-27020AF350

Alexa Fluor 405

NBP3-27020AF405

Alexa Fluor 488

NBP3-27020AF488

Alexa Fluor 532

NBP3-27020AF532

Alexa Fluor 594

NBP3-27020AF594

Alexa Fluor 647

NBP3-27020AF647

Alexa Fluor 700

NBP3-27020AF700

Alexa Fluor 750

NBP3-27020AF750

Allophycocyanin

NBP3-27020APC

Biotin

NBP3-27020B

CoraFluor 1

NBP3-27020CL1

DyLight 350

NBP3-27020UV

DyLight 405

NBP3-27020V

DyLight 488

NBP3-27020G

DyLight 550

NBP3-27020R

DyLight 594

NBP3-27020DL594

DyLight 650

NBP3-27020C

DyLight 680

NBP3-27020FR

DyLight 755

NBP3-27020IR

FITC

NBP3-27020F

HRP

NBP3-27020H

Janelia Fluor 525

NBP3-27020JF525

Janelia Fluor 549

NBP3-27020JF549

Janelia Fluor 585

NBP3-27020JF585

Janelia Fluor 635

NBP3-27020JF635

Janelia Fluor 646

NBP3-27020JF646

Janelia Fluor 669

NBP3-27020JF669

mFluor Violet 450 SE

NBP3-27020MFV450

mFluor Violet 500 SE

NBP3-27020MFV500

mFluor Violet 610 SE

NBP3-27020MFV610

PerCP

NBP3-27020PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-27020

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Mouse IgG₂ kappa Clone # TRPC6/7671

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPC6 Antibodies »

Product Summary for TRPC6 Antibody (TRPC6/7671) [PE]

Immunogen

Recombinant full-length human TRPC6 protein

Localization

Cell surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₂ kappa

Applications for TRPC6 Antibody (TRPC6/7671) [PE]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRPC6

The protein encoded by the TRPC6 gene creates receptor-activated cation permeant calcium channels in the cell membrane. Isoform 1 is 931 amino acids in length and is approximately 106 kDa, while isoform 2 is 815 amino acids in lenth at around 93 kDA. Isoform 3 is 876 amino acids long and is just over 100 kDA. Focal segmental glomerulosclerosis 2 (FSGS2) is caused by deficits in the TRPC6 gene. This gene has been linked to diseases such as cystic fibrosis, gigantism, hypertension, kidney disease, glomerulosclerosis, pyloric stenosis, diencephalic neoplasm, premature ovarian failure, and hepatopulmonary syndrome. The TRPC6 gene interacts with MX1, ORAI1, NPHS1, NPHS2, and FYN genes in pathways that monitor sodium as well as calcium channels, EPO signaling pathway, G alpha (q) signaling events, signal transduction, and platelet homeostasis.

Long Name

Short transient receptor potential channel 6

Alternate Names

FSGS2, TRP-6, TRP6

Gene Symbol

TRPC6

Additional TRPC6 Products

Product Documents for TRPC6 Antibody (TRPC6/7671) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRPC6 Antibody (TRPC6/7671) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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