TRPC6 Antibody (TRPC6/7672) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27025H

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-26742

Alexa Fluor 350

NBP3-27025AF350

Alexa Fluor 405

NBP3-27025AF405

Alexa Fluor 488

NBP3-27025AF488

Alexa Fluor 532

NBP3-27025AF532

Alexa Fluor 594

NBP3-27025AF594

Alexa Fluor 647

NBP3-27025AF647

Alexa Fluor 700

NBP3-27025AF700

Alexa Fluor 750

NBP3-27025AF750

Allophycocyanin

NBP3-27025APC

Biotin

NBP3-27025B

CoraFluor 1

NBP3-27025CL1

DyLight 350

NBP3-27025UV

DyLight 405

NBP3-27025V

DyLight 488

NBP3-27025G

DyLight 550

NBP3-27025R

DyLight 594

NBP3-27025DL594

DyLight 650

NBP3-27025C

DyLight 680

NBP3-27025FR

DyLight 755

NBP3-27025IR

FITC

NBP3-27025F

Janelia Fluor 525

NBP3-27025JF525

Janelia Fluor 549

NBP3-27025JF549

Janelia Fluor 585

NBP3-27025JF585

Janelia Fluor 635

NBP3-27025JF635

Janelia Fluor 646

NBP3-27025JF646

Janelia Fluor 669

NBP3-27025JF669

mFluor Violet 450 SE

NBP3-27025MFV450

mFluor Violet 500 SE

NBP3-27025MFV500

mFluor Violet 610 SE

NBP3-27025MFV610

PE

NBP3-27025PE

PerCP

NBP3-27025PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-27025

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

HRP

Antibody Source

Monoclonal Mouse IgG₂ kappa Clone # TRPC6/7672

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPC6 Antibodies »

Product Summary for TRPC6 Antibody (TRPC6/7672) [HRP]

Immunogen

Recombinant full-length human TRPC6 protein

Localization

Cell surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₂ kappa

Applications for TRPC6 Antibody (TRPC6/7672) [HRP]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRPC6

The protein encoded by the TRPC6 gene creates receptor-activated cation permeant calcium channels in the cell membrane. Isoform 1 is 931 amino acids in length and is approximately 106 kDa, while isoform 2 is 815 amino acids in lenth at around 93 kDA. Isoform 3 is 876 amino acids long and is just over 100 kDA. Focal segmental glomerulosclerosis 2 (FSGS2) is caused by deficits in the TRPC6 gene. This gene has been linked to diseases such as cystic fibrosis, gigantism, hypertension, kidney disease, glomerulosclerosis, pyloric stenosis, diencephalic neoplasm, premature ovarian failure, and hepatopulmonary syndrome. The TRPC6 gene interacts with MX1, ORAI1, NPHS1, NPHS2, and FYN genes in pathways that monitor sodium as well as calcium channels, EPO signaling pathway, G alpha (q) signaling events, signal transduction, and platelet homeostasis.

Long Name

Short transient receptor potential channel 6

Alternate Names

FSGS2, TRP-6, TRP6

Gene Symbol

TRPC6

Additional TRPC6 Products

Product Documents for TRPC6 Antibody (TRPC6/7672) [HRP]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for TRPC6 Antibody (TRPC6/7672) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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