TSH beta Antibody (SR1242)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21897

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21897-100ul
NBP3-21897-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1242

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TSH beta Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human TSH beta (Uniprot #: P01222)

Specificity

Detects endogenous levels of total TSH beta

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TSH beta Antibody (SR1242)

Western Blot: TSH beta Antibody (SR1242) [NBP3-21897] -

Western Blot: TSH beta Antibody (SR1242) [NBP3-21897] - Western blot analysis using NBP3-21897 in Human pituitary lysate.

Applications for TSH beta Antibody (SR1242)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSH beta

Thyroid-stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Long Name

Thyroid-stimulating Hormone Subunit beta

Alternate Names

Thyrotropin beta, TSHB

Gene Symbol

TSHB

Additional TSH beta Products

Product Documents for TSH beta Antibody (SR1242)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TSH beta Antibody (SR1242)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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