TSH beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68647

Novus Biologicals, part of Bio-Techne
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NBP2-68647
NBP2-68647-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TSH beta Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: CAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGF

Reactivity Notes

Mouse (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TSH beta Antibody

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647] - Staining of human placenta shows no positivity in trophoblastic cells as expected.
Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647] - Staining of human lower gastrointestinal shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647]

Immunohistochemistry-Paraffin: TSH beta Antibody [NBP2-68647] - Staining of human pituitary gland shows moderate to strong cytoplasmic positivity in endocrine glandular cells.
View 1 more images

Applications for TSH beta Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSH beta

Thyroid-stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Long Name

Thyroid-stimulating Hormone Subunit beta

Alternate Names

Thyrotropin beta, TSHB

Gene Symbol

TSHB

Additional TSH beta Products

Product Documents for TSH beta Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TSH beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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