TSHR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1449

Novus Biologicals, part of Bio-Techne
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NLS1449
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bat (94%), Canine (94%), Chimpanzee (94%), Equine (94%), Monkey (94%), Orangutan (94%), Porcine (94%), Primate (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all TSHR Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from C-terminus of human TSHR.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (94%), Gibbon (94%), Marmoset (94%), Mouse (89%), Rat (89%), Sheep (89%), Feline (89%), Bovine (89%), Hamster (89%), Panda (89%), Rabbit (89%), Opossum (89%).

Specificity

Human TSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LHCGR (42%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for TSHR Antibody - BSA Free

Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSHR Antibody [NLS1449] - Thyroid, Follicular Carcinoma
Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSH R Antibody [NLS1449] - Analysis of anti-TSH Receptor / TSHR antibody with human thyroid, follicular epithelium.
Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSHR Antibody - BSA Free [NLS1449]

Immunohistochemistry-Paraffin: TSH R Antibody [NLS1449] - Analysis of anti-TSH Receptor / TSHR antibody with human thyroid, follicular carcinoma.
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Applications for TSHR Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

4 - 13 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: TSHR

Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism). Multiple isoforms of the thyrotropin receptor are produced by altervative splicing. The thyrotropin receptor has been reported in adipose, adrenal, brain, eye, heart, kidney, skin, thymus, and thyroid. ESTs have been isolated from brain, placenta, and thyroid libraries.

Long Name

Thyroid Stimulating Hormone Receptor

Alternate Names

CHNG1, LGR3, TSH R

Entrez Gene IDs

7253 (Human)

Gene Symbol

TSHR

UniProt

P16473

Additional TSHR Products

Product Documents for TSHR Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TSHR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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