TSLP Antibody (55N1E3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27323

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 55N1E3

Concentration

0.5 mg/ml

View all TSLP Antibodies »

Product Summary for TSLP Antibody (55N1E3)

Immunogen

amino acids (27-158) MDYDFTNCDFEkIkAAYLSTISkDLITYMSGTkSTEFNNTVSCSNRPHCLTEIQSLTFNP~TAGCASLAkEMFAMkTkAALAIWCPGYSETQINATQAMkkRRkRkVTTNkCLEQVSQLQG~LWRRFNRPLLkQQL

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for TSLP Antibody (55N1E3)

Western Blot: TSLP Antibody (55N1E3) [NBP2-27323]

Western Blot: TSLP Antibody (55N1E3) [NBP2-27323]

Western Blot: TSLP Antibody (55N1E3) [NBP2-27323] - Analysis of TSLP partial recombinant protein (amino acids 27-158) using TSLP antibody at 0.5 ug/ml.

Applications for TSLP Antibody (55N1E3)

Application
Recommended Usage

Western Blot

0.5-2ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TSLP

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of Tcell-attracting chemokines from monocytes, enhances the maturation of CD11c+ dendritic cells, naive CD4+, and CD8+ Tcells into proallergic effectors, and primes DCs to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory Tcells and maintenance of peripheral CD4+ Tcell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. TSLP is expressed in heart, liver and prostate.

Long Name

Thymic Stromal Lymphopoietin

Alternate Names

thymic stromal lymphopoietin

Gene Symbol

TSLP

UniProt

Q969D9

Additional TSLP Products

Product Documents for TSLP Antibody (55N1E3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TSLP Antibody (55N1E3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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