TUBGCP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83380

Novus Biologicals, part of Bio-Techne
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NBP1-83380
NBP1-83380-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all TUBGCP5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSREDSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHSNLAAVW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TUBGCP5 Antibody

Immunohistochemistry-Paraffin: TUBGCP5 Antibody [NBP1-83380]

Immunohistochemistry-Paraffin: TUBGCP5 Antibody [NBP1-83380]

Immunohistochemistry-Paraffin: TUBGCP5 Antibody [NBP1-83380] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Applications for TUBGCP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TUBGCP5

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP5 (gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1,024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.

Alternate Names

gamma-tubulin complex component 5, gamma-tubulin complex component GCP5, GCP5KIAA1899GCP-5, tubulin, gamma complex associated protein 5

Gene Symbol

TUBGCP5

Additional TUBGCP5 Products

Product Documents for TUBGCP5 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for TUBGCP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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