TXNRD2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20768

Novus Biologicals, part of Bio-Techne
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NBP2-20768
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Thioredoxin Reductase 2/TRXR2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human TXNRD2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%), Rat (80%).

Localization

Mitochondrion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for TXNRD2 Antibody

Western Blot: TXNRD2 Antibody [NBP2-20768]

Western Blot: TXNRD2 Antibody [NBP2-20768]

Western Blot: TXNRD2 Antibody [NBP2-20768] - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: TXNRD2 Antibody [NBP2-20768]

Immunocytochemistry/ Immunofluorescence: TXNRD2 Antibody [NBP2-20768]

Immunocytochemistry/Immunofluorescence: TXNRD2 Antibody [NBP2-20768] - TXNRD2 antibody detects TXNRD2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37C for 30 min. Green: TXNRD2 protein stained by TXNRD2 antibody diluted at 1:500. Blue: Hoechst 33342 staining.
Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP2-20768]

Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP2-20768]

Immunohistochemistry-Paraffin: TXNRD2 Antibody [NBP2-20768] - Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using antibody at 1:500 dilution.

Applications for TXNRD2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Thioredoxin Reductase 2/TRXR2

Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq]

Alternate Names

SelZ, TR-beta, TRXR2, TXNRD2

Gene Symbol

TXNRD2

Additional Thioredoxin Reductase 2/TRXR2 Products

Product Documents for TXNRD2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TXNRD2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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