Tyk2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87825

Novus Biologicals, part of Bio-Techne
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NBP1-87825
NBP1-87825-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Tyk2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGVAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVEEEVNKEEGSSGSSGRNPQASLFGKKAKAHKAFGQPADRPREPLWAYFCDFRDITHVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Tyk2 Antibody

Western Blot: Tyk2 Antibody [NBP1-87825]

Western Blot: Tyk2 Antibody [NBP1-87825]

Western Blot: Tyk2 Antibody [NBP1-87825] - Analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: Tyk2 Antibody [NBP1-87825]

Immunocytochemistry/ Immunofluorescence: Tyk2 Antibody [NBP1-87825]

Immunocytochemistry/Immunofluorescence: Tyk2 Antibody [NBP1-87825] - Staining of human cell line U-2 OS shows localization to cytosol. Antibody staining is shown in green.

Applications for Tyk2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Tyk2

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

Long Name

Protein tyrosine kinase 2

Alternate Names

EC 2.7.10, EC 2.7.10.2, JTK1, non-receptor tyrosine-protein kinase TYK2, tyrosine kinase 2

Gene Symbol

TYK2

Additional Tyk2 Products

Product Documents for Tyk2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Tyk2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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