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Tyk2 Products

Tyk2 belongs to the Janus family of intracellular tyrosine kinases that are activated by receptors for many cytokines. Activation of Tyk2 occurs via phosphorylation at two adjacent tyrosine residues within the kinase domain. Tyk2 is required for interferon-mediated tyrosine phosphorylation of STAT3 and interferon a receptor 1. Mice lacking Tyk2 are susceptible to parasitic infection but resistant to autoimmune arthritis.

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18 results for "Tyk2" in Products

18 results for "Tyk2" in Products

Tyk2 Products

Tyk2 belongs to the Janus family of intracellular tyrosine kinases that are activated by receptors for many cytokines. Activation of Tyk2 occurs via phosphorylation at two adjacent tyrosine residues within the kinase domain. Tyk2 is required for interferon-mediated tyrosine phosphorylation of STAT3 and interferon a receptor 1. Mice lacking Tyk2 are susceptible to parasitic infection but resistant to autoimmune arthritis.

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Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human
Applications: IHC, WB, ELISA
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse
Catalog #: H00007297-Q01
Applications: WB, ELISA, MA, AP
Applications: WB, ELISA
Reactivity: Mouse, Rat
Applications: ELISA
Applications: ELISA
Catalog #: H00007297-T02
Applications: WB
Applications: AC

Potent JAK inhibitor

Potent TYK2 inhibitor

Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable

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