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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # TYRP1/1986

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary) (Uniprot: P17643)

Localization

Cytoplasmic

Marker

Melanoma Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-61599).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free [NBP2-61600]

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free [NBP2-61600]

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free [NBP2-61600] - Formalin-fixed, paraffin-embedded human Skin stained withTYRP1 Mouse Monoclonal Antibody (TYRP1/1986)
Protein Array: TYRP1 Antibody (TYRP1/1986)Azide and BSA Free [NBP2-61600]

Protein Array: TYRP1 Antibody (TYRP1/1986)Azide and BSA Free [NBP2-61600]

Protein Array: TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free [NBP2-61600] - Analysis of Protein Array containing more than 19,000 full-length human proteins using TYRP1 Antibody (TYRP1/1986). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD?s) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD?s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5.

Applications for TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free

Application
Recommended Usage

ELISA

2-4 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
ELISA: Use Ab at 2-4ug/ml for coating. Order Ab without BSA.
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: TYRP1

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq]

Alternate Names

b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP

Gene Symbol

TYRP1

Additional TYRP1 Products

Product Documents for TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TYRP1 Antibody (TYRP1/1986) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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