TYRP1 Antibody (TYRP1/3281)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07155

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # TYRP1/3281

Concentration

0.2 mg/ml

View all TYRP1 Antibodies »

Product Summary for TYRP1 Antibody (TYRP1/3281)

Immunogen

A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary) (Uniprot: P17643)

Localization

Cytoplasmic

Marker

Melanoma Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

75 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08897)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for TYRP1 Antibody (TYRP1/3281)

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/3281) [NBP3-07155]

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/3281) [NBP3-07155]

Immunohistochemistry-Paraffin: TYRP1 Antibody (TYRP1/3281) [NBP3-07155] - Formalin-fixed, paraffin-embedded human Skin stained with TYRP1-Monospecific Mouse Monoclonal Antibody (TYRP1/3281).
Protein Array: TYRP1 Antibody (TYRP1/3281) [NBP3-07155]

Protein Array: TYRP1 Antibody (TYRP1/3281) [NBP3-07155]

Protein Array: TYRP1 Antibody (TYRP1/3281) [NBP3-07155] - Analysis of Protein Array containing more than 19,000 full-length human proteins using TYRP1-Monospecific Mouse Monoclonal Antibody (TYRP1/3281).

Applications for TYRP1 Antibody (TYRP1/3281)

Application
Recommended Usage

ELISA

2-4 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
ELISA: Use Ab at 2-4ug/ml for coating. Order Ab without BSA.
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: TYRP1

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq]

Alternate Names

b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP

Gene Symbol

TYRP1

UniProt

P17643 (Human)

Additional TYRP1 Products

Product Documents for TYRP1 Antibody (TYRP1/3281)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TYRP1 Antibody (TYRP1/3281)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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