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UBR5/EDD Antibody (SR1501)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22217

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
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NBP3-22217-100ul
NBP3-22217-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1501

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for UBR5/EDD Antibody (SR1501)

Immunogen

A synthesized peptide derived from human UBR5/EDD (Uniprot #: O95071)

Specificity

Detects endogenous levels of total UBR5/EDD

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

309 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for UBR5/EDD Antibody (SR1501)

Western Blot: UBR5/EDD Antibody (SR1501) [NBP3-22217] -

Western Blot: UBR5/EDD Antibody (SR1501) [NBP3-22217] - Western blot analysis using NBP3-22217 in SH-SY5Y cell lysate.

Applications for UBR5/EDD Antibody (SR1501)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UBR5

EDD encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Long Name

Ubiquitin Protein Ligase E3 Component N-recognin 5

Alternate Names

DD5, EDD, EDD1, HYD

Gene Symbol

UBR5

Additional UBR5 Products

Product Documents for UBR5/EDD Antibody (SR1501)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for UBR5/EDD Antibody (SR1501)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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