UMPS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-20810

Novus Biologicals, part of Bio-Techne
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NBP2-20810
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all UMPS Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human UMPS. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (81%), Bovine (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for UMPS Antibody

Western Blot: UMPS Antibody [NBP2-20810]

Western Blot: UMPS Antibody [NBP2-20810]

Western Blot: UMPS Antibody [NBP2-20810] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: UMPS Antibody [NBP2-20810]

Immunocytochemistry/ Immunofluorescence: UMPS Antibody [NBP2-20810]

Immunocytochemistry/Immunofluorescence: UMPS Antibody [NBP2-20810] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: UMPS Antibody [NBP2-20810]

Immunohistochemistry-Paraffin: UMPS Antibody [NBP2-20810]

Immunohistochemistry-Paraffin: UMPS Antibody [NBP2-20810] - Immunohistochemical analysis of paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Applications for UMPS Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: UMPS

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq]

Alternate Names

EC 4.1.1.23, OMPdecase, OPRT, OPRTase, orotate phosphoribosyltransferase, orotidine 5'-phosphate decarboxylase, UMP synthase, uridine 5'-monophosphate synthase, uridine monophosphate synthetase

Gene Symbol

UMPS

UniProt

P11172 (Human)

Additional UMPS Products

Product Documents for UMPS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for UMPS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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