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Uricase Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2022

Novus Biologicals, part of Bio-Techne
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NB100-2022-0.1mg

Key Product Details

Species Reactivity

Bacteria

Applications

ELISA, Immunoprecipitation, Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

Uricase [Bacillus species] (Uniprot: Q5WBJ3)

Reactivity Notes

Reactive with Uricase from Bacillus species.
Cross reactivity against Uricase from other sources is unknown

Localization

Cytoplasmic

Specificity

Cross reactivity against Uricase from other sources is unknown.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Store vial at 4C prior to restoration. For extended storage aliquot contents and freeze at -20C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.

This antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin, anti-Goat Serum as well as purified and partially purified Uricase [Bacillus species]

Scientific Data Images for Uricase Antibody [Biotin]

Western Blot: Uricase Antibody [HRP] [NB100-2022] - Lane 1: Uricase (Bacillus). Load: 50 ng per lane. Primary antibody: Goat anti-Uricase Antibody (Bacillus Species) Biotin Conjugated at 1:1,000 overnight at 4C. Secondary antibody: HRP streptavidin secondary antibody at 1:40,000 for 30 min at RT. Block: incubated with blocking buffer for 30 min at RT. Predicted/Observed size: 39 kDa, 39 kDa for Uricase.
Western Blot: Uricase Antibody [HRP] [NB100-2022] - Lane 1: purified Uricase under reducing conditions. Lane 2: purified Uricase under reducing conditions. Lane 3: purified Uricase under non-reducing conditions. Lane 4: purified Uricase under non-reducing conditions Load: ~1.0 ug (Lane 1 and 3) and 0.25 ug (Lane 2 and 4). Primary antibody: Uricase Peroxidase conjugated Antibody at 1:5,000 overnight at 4C. Secondary antibody: DyLight (TM) 649 goat secondary antibody at 1:10,000 for 90 min at RT. Block: 5% BLOTTO overnight at 4C. Predicted/Observed size: 58 kDa, 58 kDa for Uricase. Other band(s): Uricase splice variants and isoforms.

Applications for Uricase Antibody [Biotin]

Application
Recommended Usage

ELISA

1:5000 - 1:20000

Immunoprecipitation

1:100

Western Blot

1:500 - 1:5000
Application Notes
This product has been tested by ELISA and western blot. This product is suitable to be assayed against 1.0 ug of Uricase in a standard capture ELISA using Peroxidase Conjugated Streptavidin and ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) as a substrate for 30 minutes at room temperature. A working dilution of 1:4,000 to 1:53,000 of the reconstitution concentration is suggested for This product .

Formulation, Preparation, and Storage

Purification

Multi-step

Reconstitution

Reconstitute with 100 ul deionized water (or equivalent)

Formulation

Lyophilized from 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

Preservative

0.01% Sodium Azide

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store lyophilized antibody at 4C in the dark. Aliquot reconstituted liquid and store at -20C. Avoid freeze-thaw cycles.

Background: Uricase

Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.

Alternate Names

UOXP, urate oxidase, pseudogene, URICASE

Gene Symbol

UOX

UniProt

Additional Uricase Products

Product Documents for Uricase Antibody [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Uricase Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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