USP20 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14514

Novus Biologicals, part of Bio-Techne
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NBP3-14514
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bat (94%), Bovine (94%), Canine (100%), Equine (100%), Hamster (100%), Monkey (100%), Mouse (94%), Orangutan (94%), Primate (100%), Rabbit (100%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all USP20 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from internal region of human USP20.

Epitope

Internal

Reactivity Notes

Expected reactivity based on percent sequence identity: Opossum (89%), Turkey, Chicken (83%)

Specificity

Human USP20. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for USP20 Antibody

Immunohistochemistry-Paraffin: USP20 Antibody [NBP3-14514]

Immunohistochemistry-Paraffin: USP20 Antibody [NBP3-14514]

Immunohistochemistry-Paraffin: USP20 Antibody [NBP3-14514] - Immunohistochemistry of formalin-fixed, paraffin-embedded human adrenal medulla after heat-induced antigen retrieval.

Applications for USP20 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: USP20

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Long Name

Ubiquitin Specific Protease 20

Alternate Names

LSFR3A, Ubiquitin Thiolesterase 20, VDU2

Gene Symbol

USP20

Additional USP20 Products

Product Documents for USP20 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for USP20 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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