USP24 Antibody (SR1479)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22428

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22428-100ul
NBP3-22428-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1479

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all USP24 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human USP24 (Uniprot #: Q9UPU5)

Specificity

Detects endogenous levels of total USP24

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

294 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for USP24 Antibody (SR1479)

Western Blot: USP24 Antibody (SR1479) [NBP3-22428] -

Western Blot: USP24 Antibody (SR1479) [NBP3-22428] - Western blot analysis using NBP3-22428 in HeLa cell lysate.

Applications for USP24 Antibody (SR1479)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: USP24

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Long Name

Ubiquitin Specific Protease 24

Alternate Names

Deubiquitinating enzyme 24, EC 3.4.19.12, FLJ31309, KIAA1057ubiquitin carboxyl-terminal hydrolase 24, ubiquitin specific peptidase 24, ubiquitin specific protease 24, ubiquitin thioesterase 24, Ubiquitin thiolesterase 24, ubiquitin-specific processing protease 24, Ubiquitin-specific-processing protease 24

Gene Symbol

USP24

Additional USP24 Products

Product Documents for USP24 Antibody (SR1479)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for USP24 Antibody (SR1479)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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