Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all USP33 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 900 and the C-terminus (residue 942) of human Ubiquitin Specific Peptidase 33 using the numbering given in entry NP_055832.3 (GeneID 23032).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for USP33 Antibody

Western Blot: USP33 Antibody [NB110-40693]

Western Blot: USP33 Antibody [NB110-40693]

Western Blot: USP33 Antibody [NB110-40693] - Detection of Human USP33 on HeLa whole cell lysate using NB110-40693. USP33 was also immunoprecipitated by rabbit anti-USP33 antibody NB110-40692.
Immunohistochemistry: USP33 Antibody [NB110-40693]

Immunohistochemistry: USP33 Antibody [NB110-40693]

Immunohistochemistry: USP33 Antibody [NB110-40693] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti- USP33 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: USP33 Antibody [NB110-40693]

Immunohistochemistry-Paraffin: USP33 Antibody [NB110-40693]

Immunohistochemistry-Paraffin: USP33 Antibody [NB110-40693] - FFPE section of human breast carcinoma. Affinity purified rabbit anti-USP33 used at a dilution of 1:250.
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Applications for USP33 Antibody

Application
Recommended Usage

Immunohistochemistry

1:250

Immunohistochemistry-Paraffin

1:250

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: USP33

A novel protein named VHL-interacting deubiquitinating enzyme 1 (VDU1/USP33) was identified as being able to directly interact with pVHL in vitro and in vivo. The VDU1-interacting region in pVHL is located in its beta-domain, and several naturally occurring mutations located in this domain disrupt the interaction between pVHL and VDU1 protein. VDU1 is able to be ubiquitinated via a pVHL-dependent pathway for proteasomal degradation.

Long Name

Ubiquitin carboxyl-terminal hydrolase 33

Alternate Names

hVDU1, KIAA1097, VDU1

Entrez Gene IDs

23032 (Human)

Gene Symbol

USP33

UniProt

Q8TEY7 (Human)

Additional USP33 Products

Product Documents for USP33 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for USP33 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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