Utrophin Antibody (5G6)

Novus Biologicals, part of Bio-Techne | Catalog # H00007402-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 5G6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Utrophin Antibodies »

Product Specifications

Immunogen

UTRN (NP_009055, 3328 a.a. ~ 3433 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LEARMQILEDHNKQLESQLHRLRQLLEQPESDSRINGVSPWASPQHSALSYSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPSCCPNVPSRPQAM

Specificity

UTRN - utrophin (homologous to dystrophin)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Utrophin Antibody (5G6)

Immunocytochemistry/ Immunofluorescence: Utrophin Antibody (5G6) [H00007402-M01]

Immunocytochemistry/ Immunofluorescence: Utrophin Antibody (5G6) [H00007402-M01]

Immunocytochemistry/Immunofluorescence: Utrophin Antibody (5G6) [H00007402-M01] - Analysis of monoclonal antibody to UTRN on HeLa cell . Antibody concentration 10 ug/ml.
ELISA: Utrophin Antibody (5G6) [H00007402-M01]

ELISA: Utrophin Antibody (5G6) [H00007402-M01]

ELISA: Utrophin Antibody (5G6) [H00007402-M01] - Detection limit for recombinant GST tagged UTRN is 0.1 ng/ml as a capture antibody.

Applications for Utrophin Antibody (5G6)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Utrophin

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined.

Alternate Names

DMDLutrophin (homologous to dystrophin), DRP, DRP1DRP-1, Dystrophin-related protein 1, FLJ23678, utrophin

Entrez Gene IDs

7402 (Human)

Gene Symbol

UTRN

OMIM

128240 (Human)

UniProt

NP_009055 (Human)

Additional Utrophin Products

Product Documents for Utrophin Antibody (5G6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Utrophin Antibody (5G6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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