VAMP-7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80709

Novus Biologicals, part of Bio-Techne
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NBP1-80709
NBP1-80709-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Predicted:

Mouse (98%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VAMP-7 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YAMNSEFSSVLAAQLKHHSENKGLDKVMETQAQVDELKGIMVRNIDLVAQRGERLELLIDKTENLVDSSVTFKTTSRNLARAMCMKNL

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24880616).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VAMP-7 Antibody

Immunocytochemistry/ Immunofluorescence: VAMP-7 Antibody [NBP1-80709]

Immunocytochemistry/ Immunofluorescence: VAMP-7 Antibody [NBP1-80709]

Immunocytochemistry/Immunofluorescence: VAMP-7 Antibody [NBP1-80709] - Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: VAMP-7 Antibody [NBP1-80709]

Immunohistochemistry-Paraffin: VAMP-7 Antibody [NBP1-80709]

Immunohistochemistry-Paraffin: VAMP-7 Antibody [NBP1-80709] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for VAMP-7 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC reported in scientific literature (PMID: 24880616). For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VAMP-7

Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.

Long Name

Vesicle-Associated Membrane Protein 7

Alternate Names

SYBL1, TI-VAMP, VAMP7

Entrez Gene IDs

6845 (Human)

Gene Symbol

VAMP7

UniProt

P51809 (Human)

Additional VAMP-7 Products

Product Documents for VAMP-7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VAMP-7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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