Vang-like Protein 2/VANGL2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-59736

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Mouse

Predicted:

Bovine (100%), Human (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Vang-like Protein 2/VANGL2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QKYLRTTKQQPYH corresponding to internal region according to NP_065068.1.

Epitope

QKYLRTTKQQPYH

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Vang-like Protein 2/VANGL2 Antibody

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NB100-59736]

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NB100-59736]

Western Blot: Vang-like Protein 2/VANGL2 Antibody [NB100-59736] - Staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Vang-like Protein 2/VANGL2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx 55 kDa band observed in mouse brain lysates (calculated MW of 59.7kDa according to NP_065068.1).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Vang-like Protein 2/VANGL2

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Alternate Names

LPP1, LTAP, STB1, STBM, Strabismus, Vang like Protein 2, VANGL2

Entrez Gene IDs

57216 (Human); 93840 (Mouse)

Gene Symbol

VANGL2

UniProt

Q9ULK5

Additional Vang-like Protein 2/VANGL2 Products

Product Documents for Vang-like Protein 2/VANGL2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Vang-like Protein 2/VANGL2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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