Vanilloid R1/TRPV1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-71774

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse, Primate, Primate - Callithrix jacchus (Common Marmoset)

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all Vanilloid R1/TRPV1 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to a C-terminal region of the human TRPV1 protein (within residues 725-839). [Swiss-Prot# Q8NER1]

Localization

Cell junction: synapse. Multi-pass membrane protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vanilloid R1/TRPV1 Antibody - BSA Free

Immunohistochemistry: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunohistochemistry: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - The Vanilloid R1/TRPV1+ and Vanilloid R1/TRPV1+CD4+ immune cells in patients with allergic rhinitis. Immunohistochemical staining of Vanilloid R1/TRPV1 (single staining) and CD4/Vanilloid R1/TRPV1 (double staining) in patients with allergic rhinitis compared with control subjects. Image collected and cropped by CiteAb from the following publication (https://www.oncotarget.com/fulltext/6653), licensed under a CC-BY license.
Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunocytochemistry/Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - TRPV1 antibody was tested at 1:50 in HeLa cells with FITC (green). Nuclei were counterstained with DAPI (blue).
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunohistochemistry: Vanilloid R1/TRPV1 Antibody - BSA Free [NBP1-71774]

Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - Analysis of TRPV1 in mouse dorsal root ganglion using DAB with hematoxylin counterstain.
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Applications for Vanilloid R1/TRPV1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:100

Immunohistochemistry

1:200

Immunohistochemistry-Paraffin

1:200
Application Notes
This TRPV1 antibody is useful for ICC/IF and IHC-paraffin embedded tissues. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP1-71774 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Vanilloid R1/TRPV1

TRPV1, a ligand-gated cation channel expressed in peripheral nociceptors, induces pain when activated by capsaicin. TRPV1 affects the inhibitory control of neurons by integrating multiple noxious signals, which is critical in chronic pain. Blocking TRPV1 is becoming a more common approach to suppression of pathological pain. When inflammation is present, TRPV1 causes an itch response. Dietary salt content can affect the concentration and activity of TRPV1, which in turn can affect kidney activities resulting in renin regulation. TRPV1 is also critically involved in thermal activation and detection of infrared radiation. Finally, TRPV1 is dysfunctional in hypertrophic hearts.

Long Name

Vanilloid Receptor 1/Transient Receptor Potential Cation Channel 1

Alternate Names

Capsaicin Receptor, TRPV1, VanilloidR1, VR1

Entrez Gene IDs

7442 (Human)

Gene Symbol

TRPV1

UniProt

Q8NER1 (Human)

Additional Vanilloid R1/TRPV1 Products

Product Documents for Vanilloid R1/TRPV1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Vanilloid R1/TRPV1 Antibody - BSA Free

Manufactured by Genomic Antibody Technology™. GAT FAQs

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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