VDR/NR1I1/Vitamin D Receptor Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98840

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all VDR/NR1I1 Antibodies »

Product Summary for VDR/NR1I1/Vitamin D Receptor Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the human VDR/NR1I1/Vitamin D Receptor.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for VDR/NR1I1/Vitamin D Receptor Antibody

Immunohistochemistry-Paraffin: VDR/NR1I1/Vitamin D Receptor Antibody [NBP2-98840]

Immunohistochemistry-Paraffin: VDR/NR1I1/Vitamin D Receptor Antibody [NBP2-98840]

Immunohistochemistry-Paraffin: VDR/NR1I1/Vitamin D Receptor Antibody [NBP2-98840] - Immunochemical staining of human VDR/NR1I1/Vitamin D Receptor in human pancreas with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).

Applications for VDR/NR1I1/Vitamin D Receptor Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:1000-1:4000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VDR/NR1I1

Vitamin D Receptor encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

Long Name

Vitamin D [1,25-Dihydroxyvitamin D3] Receptor

Alternate Names

NR1I1

Gene Symbol

VDR

Additional VDR/NR1I1 Products

Product Documents for VDR/NR1I1/Vitamin D Receptor Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VDR/NR1I1/Vitamin D Receptor Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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