VEGFR1/Flt-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-685

Novus Biologicals, part of Bio-Techne
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NB100-685
NB100-685-0.1ml
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all VEGFR1/Flt-1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide: C-AELERKIACCSPPPDYN, corresponding to amino acids 1312-1328 of human VEGF Receptor 1 (C-terminus).

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Rat.

Localization

Cytoplasmic

Specificity

This reacts with a 180 kD protein, known as VEGFR1/Flt-1 or vascular endothelial growth factor receptor 1. VEGFR1/Flt-1 is a cell membrane receptor kinase. VEGFR1/Flt-1 has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Marker

Endothelial Cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VEGFR1/Flt-1 Antibody

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry-Paraffin: VEGFR1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human placenta stained with VEGFR1/Flt-1 antibody (NB100-685).
Immunohistochemistry: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry: VEGFR1/Flt-1 Antibody [NB100-685]

Immunohistochemistry: VEGF R1/Flt-1 Antibody [NB100-685] - Formalin fixed paraffin embedded human angiosarcoma stained with Flt-1.

Applications for VEGFR1/Flt-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:25-1:50

Immunohistochemistry-Frozen

1:50-1:100

Immunohistochemistry-Paraffin

1:25-1:50
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 0.2% BSA, Tween-20

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: VEGFR1/Flt-1

The receptor for VEGF, VEGFB and PGF has tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis. VEGFR 1 is a cell membrane receptor kinase. It has a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Long Name

Vascular Endothelial Growth Factor Receptor 1

Alternate Names

Flt-1, FLT1, FRT, VEGF R1, VEGFR-1

Entrez Gene IDs

2321 (Human); 14254 (Mouse); 54251 (Rat)

Gene Symbol

FLT1

UniProt

P17948

Additional VEGFR1/Flt-1 Products

Product Documents for VEGFR1/Flt-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VEGFR1/Flt-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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