VGLUT2 Antibody (CL2952)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46641

Novus Biologicals, part of Bio-Techne
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NBP2-46641
NBP2-46641-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse, Rat, Rhesus Macaque

Cited:

Primate - Macaca mulatta (Rhesus Macaque)

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL2952

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all VGLUT2 Antibodies »

Product Specifications

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence CGFIHEDELDEETGDITQNYINYGTTKSYGATTQANGGWPSGWEKKEEFVQGEVQDSHSYKDRVDY

Epitope

NGGWPSGWEK

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions. Use in Rhesus Macaque reported in scientific publication (PMID: 32337749).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for VGLUT2 Antibody (CL2952)

Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Analysis in human cerebral cortex and tonsil tissues using NBP2-46641 antibody. Corresponding VGLUT2 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry-Paraffin: VGLUT2 Antibody (CL2952) [NBP2-46641] - Staining of human kidney shows absence of immunoreactivity (negative control).
Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641]

Immunohistochemistry: VGLUT2 Antibody (CL2952) [NBP2-46641] - VGLUT2 Antibody (2952) [NBP2-46641] - Staining of rat thalamus shows strong immunoreactivity in glutamatergic synapses.
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Applications for VGLUT2 Antibody (CL2952)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Frozen

Reported in scientific publication (PMID: 32337749)

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VGLUT2

VGLUT2 is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.

Alternate Names

differentiation-associated BNPI, differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, differentiation-associated Na-dependent inorganic phosphate cotransporter, DNPI, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, solute carrier family 17 member 6, vesicular glutamate transporter 2, VGLUT2

Entrez Gene IDs

57084 (Human)

Gene Symbol

SLC17A6

UniProt

Q9P2U8 (Human)

Additional VGLUT2 Products

Product Documents for VGLUT2 Antibody (CL2952)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VGLUT2 Antibody (CL2952)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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