Virilizer Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85118

Novus Biologicals, part of Bio-Techne
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NBP1-85118
NBP1-85118-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Virilizer Antibodies »

Product Summary for Virilizer Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDISVALNTRKL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Virilizer Antibody

Immunocytochemistry/ Immunofluorescence: Virilizer Antibody [NBP1-85118]

Immunocytochemistry/ Immunofluorescence: Virilizer Antibody [NBP1-85118]

Immunocytochemistry/Immunofluorescence: Virilizer Antibody [NBP1-85118] - Staining of human cell line U-2 OS shows localization to nucleoplasm, nuclear bodies & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118]

Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118]

Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118]

Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118]

Immunohistochemistry-Paraffin: Virilizer Antibody [NBP1-85118] - Staining of human rectum shows moderate nuclear positivity in glandular cells.
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Applications for Virilizer Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Virilizer

The virilizer (vir) gene was discovered as a factor required for dosage compensation and sex determination in female flies. In drosophila it has been determined to function as a positive regulator of female-specific mRNA splicing. Database searches using the deduced amino acid sequence of the drosophila VIR retrieved a human protein BAA92667 (GenBank) which corresponds to the gene designated as KIAA1429. The human protein is 28% identical and about 40% similar to drosophila VIR and contains the putative transmembrane domain of drosophila VIR.

Alternate Names

DKFZp434I116, DKFZp781B2117, fSAP121, functional spliceosome-associated protein 121, KIAA1429, MGC138493, MGC141940, protein virilizer homolog

Gene Symbol

VIRMA

Additional Virilizer Products

Product Documents for Virilizer Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Virilizer Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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