VMAT2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1479

Novus Biologicals, part of Bio-Techne
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NB100-1479
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all VMAT2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SYPIGEDEESESD corresponding to C-Terminus according to NP_003045.2.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 30567483).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for VMAT2 Antibody

Western Blot: VMAT2 Antibody [NB100-1479]

Western Blot: VMAT2 Antibody [NB100-1479]

Western Blot: VMAT2 Antibody [NB100-1479] - (2ug/ml) staining of Human Adrenal Gland lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.
Immunohistochemistry: VMAT2 Antibody [NB100-1479]

Immunohistochemistry: VMAT2 Antibody [NB100-1479]

Immunohistochemistry: VMAT2 Antibody [NB100-1479] - Negative Control showing staining of paraffin embedded Human Adrenal Gland, with no primary antibody.
Immunohistochemistry: VMAT2 Antibody [NB100-1479]

Immunohistochemistry: VMAT2 Antibody [NB100-1479]

Immunohistochemistry: VMAT2 Antibody [NB100-1479] - (6ug/ml) staining of paraffin embedded Human Adrenal Gland. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for VMAT2 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 - 6 ug/ml

Peptide ELISA

Detection limit 1:8000

Western Blot

1 - 3 ug/mL
Application Notes
ICC/IF reactivity reported in scientific literature (PMID: 30567483).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: VMAT2

VMAT2 (Vesicular amine transporter 2) acts to accumulate cytosolic monoamines into synaptic vesicles. Its function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders such as dementia with Lewy bodies. The transporter is a site of action of important drugs, including reserpine and tetrabenazine.

Long Name

Vesicular Monoamine Transporter 2/Solute Carrier Family 18, Member 2

Alternate Names

MNAT, SLC18A2, SVAT, SVMT, VAT2

Entrez Gene IDs

6571 (Human); 214084 (Mouse); 25549 (Rat)

Gene Symbol

SLC18A2

UniProt

Q05940

Additional VMAT2 Products

Product Documents for VMAT2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VMAT2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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