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vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27026

Novus Biologicals, part of Bio-Techne
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NBP3-27026

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # VWF/4458

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Summary for vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

Immunogen

Recombinant full-length human vWF-A2 (exact sequence is proprietary)

Localization

Secreted

Specificity

This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

vWF-A2 Antibody (VWF/4458)

Immunohistochemistry-Paraffin: vWF-A2 Antibody (VWF/4458) - Azide and BSA Free [NBP3-27026] -

Formalin-fixed, paraffin-embedded human tonsil stained with vWF-A2 Antibody (VWF/4458) - Azide and BSA Free. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Applications for vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml for 30 minutes at RT
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: vWF-A2

Human vWF is a serum glycoprotein that mediates platelet adhesion to injured vascular endothelium. vWF function is regulated by ADAMTS13 mediated proteolysis within the A2 domain. Mutations of this protease cause thrombotic thrombocytopenic purpura.

Long Name

von Willebrand Factor A2 Domain

Alternate Names

F8VWF, vWFA2

Gene Symbol

VWF

Additional vWF-A2 Products

Product Documents for vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for vWF-A2 Antibody (VWF/4458) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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