XAB1 Antibody (3E1)

Novus Biologicals, part of Bio-Techne | Catalog # H00011321-M01

Novus Biologicals, part of Bio-Techne
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H00011321-M01
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3E1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all XAB1 Antibodies »

Product Specifications

Immunogen

XAB1 (AAH07451, 9 a.a. ~ 118 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ELQASGGPRHPVCLLVLGMAGSGKTTFVQRLTGHLHAQGTPPYVINLDPAVHEVPFPANIDIRDTVKYKEVMKQYGLGPNGGIVTSLNLFATRFDQVMKFIEKAQNMSKY

Reactivity Notes

Human. Other species not tested.

Specificity

XAB1 - XPA binding protein 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for XAB1 Antibody (3E1)

Western Blot: XAB1 Antibody (3E1) [H00011321-M01]

Western Blot: XAB1 Antibody (3E1) [H00011321-M01]

Western Blot: XAB1 Antibody (3E1) [H00011321-M01] - XAB1 monoclonal antibody (M01), clone 3E1 Analysis of XAB1 expression in HL-60.
Immunocytochemistry/ Immunofluorescence: XAB1 Antibody (3E1) [H00011321-M01]

Immunocytochemistry/ Immunofluorescence: XAB1 Antibody (3E1) [H00011321-M01]

Immunocytochemistry/Immunofluorescence: XAB1 Antibody (3E1) [H00011321-M01] - Analysis of monoclonal antibody to XAB1 on HeLa cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: XAB1 Antibody (3E1) [H00011321-M01]

Immunohistochemistry-Paraffin: XAB1 Antibody (3E1) [H00011321-M01]

Immunohistochemistry-Paraffin: XAB1 Antibody (3E1) [H00011321-M01] - Analysis of monoclonal antibody to XAB1 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
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Applications for XAB1 Antibody (3E1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: XAB1

The DNA methylation system is composed of methyl-CpG-binding proteins, as well as of DNA cytosine methyl transferases. Five methyl-CpG binding proteins were isolated: MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 consists of two isoforms, MBD2a and MBD2b, which are generated from a single gene. MBD2a is a component of MeCP1, a large corepressor complex that represses transcription from densely methylated genes. Components of MeCP1 include MBD2, Mi-2, MTA2, MBD3 and HDAC1/2. MIZF and MBDin were isolated as proteins interacting with MBD2. MBDin, in turn, is identical to XPA binding protein 1 (XAB1). At the N erminus, the protein contains the consensus sequence for a GTP binding site. At the C terminus, the protein is characterized by an acidic domain containing a cluster of acidic amino acid residues. The transcriptional repression by MBD2 at methylated promoters is relieved by MBdin. XAB1 is expressed ubiquitously, and may be involved in nuclear localization of XPA.

Alternate Names

ATP(GTP)-binding protein, ATPBD1A, GPN-loop GTPase 1, GTPase, MBD2-interacting protein, MBDin, MBDINXPA binding protein 1, XAB1FLJ51176, XPA-binding protein 1

Entrez Gene IDs

11321 (Human)

Gene Symbol

GPN1

UniProt

AAH07451 (Human)

Additional XAB1 Products

Product Documents for XAB1 Antibody (3E1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for XAB1 Antibody (3E1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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