Endoglin/CD105 Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79580

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

31.25-2000 pg/ml (example only; lot dependent)

Sensitivity

31.25 pg/ml (example only; lot dependent)

Reactivity

Mouse

View all Endoglin/CD105 ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Mouse Endoglin/CD105.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for Endoglin/CD105 Antibody Pair [HRP]

Sandwich ELISA: Endoglin/CD105 Antibody Pair [HRP] [NBP2-79580] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for Endoglin/CD105 Antibody Pair [HRP]

  • Rabbit Monoclonal Capture Antibody: (Catalog # NBP2-90572)
  • Rabbit Monoclonal Detection Antibody (HRP-conjugated): (Catalog # NBP2-90571)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Endoglin/CD105

CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.

Alternate Names

CD105, ENG

Gene Symbol

ENG

Additional Endoglin/CD105 Products

Product Documents for Endoglin/CD105 Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Endoglin/CD105 Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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