Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
473 results for "Endoglin/CD105" in Products
473 results for "Endoglin/CD105" in Products
Endoglin/CD105 Products
Endoglin (CD105) is a transmembrane type III receptor for TGF-beta superfamily ligands and plays an important role in smooth muscle differentiation, angiogenesis, and neovascularization. It is highly expressed on proliferating vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. Human Endoglin haploinsufficiency can a cause the vascular disorder, hereditary hemorrhagic telangiectasia type I. Elevated levels of anti-angiogenic soluble Endoglin contribute to pathogenicity in preeclampsia. Endoglin associates with the receptors TGF-beta RII, Activin RIIA or RIIB, BMPR-IA/ALK-3, or BMPR-IB/ALK6 and enhance binding of Activin A, BMP-2, -7, -9, TGF-beta 1, or TGF-beta 3. Endoglin can either enhance or inhibit signaling through these receptor complexes.
Simple Plex Human Endoglin/CD105 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, CyTOF-ready, +2 More |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, CyTOF-ready, +1 More |
Control for use with Human Endoglin/CD105 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166707 |
| Applications: | Flow |
| Sensitivity: | 0.03 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | WB, Flow, IHC, CyTOF-ready, ICC |
| Sensitivity: | 13.6 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166707 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #3A9 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Endoglin/CD105 Antibody (3A9)BSA Free [NBP2-22122]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-3A9-Western-Blot-NBP2-22122-img0006.jpg "Western Blot: Endoglin/CD105 Antibody (3A9)BSA Free [NBP2-22122]")
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Reactivity: | Human, Porcine, Canine (Negative), Equine (Negative) |
| Details: | Mouse IgG2A Monoclonal Clone #MEM-229 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Immunocytochemistry/ Immunofluorescence: Endoglin/CD105 Antibody (MEM-229) - BSA Free [NB110-58718]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-MEM-229-Immunofluorescence-NB110-58718-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Endoglin/CD105 Antibody (MEM-229) - BSA Free [NB110-58718]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, IHC |
| Reactivity: | Mouse, Rat |
| Details: | Rat IgG2a Kappa Monoclonal Clone #MJ7/18 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: Endoglin/CD105 Antibody (MJ7/18) [NB100-77666]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-MJ7-18-Western-Blot-NB100-77666-img0001.jpg "Western Blot: Endoglin/CD105 Antibody (MJ7/18) [NB100-77666]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166707 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166707 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP, ICC |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #MEM-226 |
| Applications: | WB, Flow, IP, CyTOF-ready |
![Flow Cytometry: Endoglin/CD105 Antibody (MEM-226) - BSA Free [NB500-452]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-MEM-226-Flow-Cytometry-NB500-452-img0009.jpg "Flow Cytometry: Endoglin/CD105 Antibody (MEM-226) - BSA Free [NB500-452]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166709 |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | NP_001010968 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #209701 |
| Applications: | Flow |
Clone SN6 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #SN6 |
| Applications: | IHC, WB, Flow, IP |
![Flow Cytometry: Endoglin/CD105 Antibody (SN6) - BSA Free [NB100-65601]](https://resources.bio-techne.com/images/products/Endoglin-CD105-Antibody-SN6-Flow-Cytometry-NB100-65601-img0008.jpg "Flow Cytometry: Endoglin/CD105 Antibody (SN6) - BSA Free [NB100-65601]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #166707 |
| Applications: | Flow |