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Mouse GSDMDC1 ELISA Kit (Colorimetric)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43460

Novus Biologicals, part of Bio-Techne
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NBP3-43460

Key Product Details

Sample Type & Volume Required Per Well

Cell Extracts

Product Specifications

Assay Type

Sandwich ELISA

Kit Type

ELISA Kit (Colorimetric)

Reactivity

Mouse

Specificity

This ELISA is specific for the measurement of natural and recombinant mouse Gasdermin D (full-length and C-terminus cleaved fragment). It does not detect human Gasdermin D. Gasdermin D is tested from supernatants of Bone Marrow-Derived Macrophages cells (BMDMs) transfected with LPS from different knockout mice strains (see figure 1). Only the supernatants from WT and NLRP3-/- strains contain the protein Gasdermin D. Gasdermin D is also tested from cell extracts (lysed with a Triton X-100 buffer) of Bone Marrow-Derived Macrophages cells from WT and Gasdermin D knockout mice strains (Figure 2). Both figures confirm the specificity of the Gasdermin (mouse) ELISA Kit.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: GSDMDC1

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation ofepithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively splicedtranscript variants have been described. (provided by RefSeq)

Long Name

Gasdermin-D

Alternate Names

DFNA5L, FKSG10, GSDMD, hGSDMD-CTD)

Gene Symbol

GSDMD

Additional GSDMDC1 Products

Product Documents for Mouse GSDMDC1 ELISA Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mouse GSDMDC1 ELISA Kit (Colorimetric)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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