Progranulin/PGRN Antibody Pair [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79289

Novus Biologicals, part of Bio-Techne
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Key Product Details

Assay Type

Sandwich ELISA

Assay Range

62.5-4000 pg/ml (example only; lot dependent)

Sensitivity

62.5 pg/ml (example only; lot dependent)

Reactivity

Human

View all Progranulin/PGRN ELISA Kits »

Product Specifications

Description

Solid Phase sandwich ELISA for the quantitative determination of Human Progranulin/PGRN.

Sample Volume Required

100 ul

Conjugate

HRP

Scientific Data Images for Progranulin/PGRN Antibody Pair [HRP]

Sandwich ELISA: Progranulin/PGRN Antibody Pair [HRP] [NBP2-79289] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Kit Contents for Progranulin/PGRN Antibody Pair [HRP]

  • Mouse Monoclonal Capture Antibody
  • Mouse Monoclonal Detection Antibody (HRP-conjugated)
  • Standard

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: Progranulin/PGRN

Progranulin, also known as Acrogranin, PCDGF, and Epithelin/Granulin Precursor, is a widely expressed glycoprotein that can undergo proteolysis to generate numerous Granulin peptides. Progranulin plays a role in the regulation of mesothelial differentiation, macrophage development, sexual differentiation of the brain, cartilage proliferation, wound repair, and the development of rheumatoid arthritis and osteoarthritis. It is often upregulated in cancer and contributes to tumor progression. Progranulin upregulation or mutation is associated with several neurological disorders including frontotemporal dementia, Creutzfeldt-Jakob disease, Alzheimer’s disease, and motor neuron disease.

Alternate Names

Acrogranin, GEP, GP88, GRN, PCDGF, PEPI, PGRN, Proepithelin

Gene Symbol

GRN

Additional Progranulin/PGRN Products

Product Documents for Progranulin/PGRN Antibody Pair [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Progranulin/PGRN Antibody Pair [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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