6 TMR Tre

Name: 6 TMR Tre
Brand: Tocris Bioscience
SKU: 6802

Tocris Bioscience, part of Bio-Techne | Catalog # 6802

Citations (1)

COA / SDS

Fluorescent trehalose; selectively labels mycobacterial cell envelope

Key Product Details

Description:	Fluorescent trehalose; selectively labels mycobacterial cell envelope
Chemical Name:	6-[4(3)-[3,6-bis(dimethylamino)xanthylium-9-yl]-3(4)-carboxybenzoyl]amino-6-deoxy-α,α-D-trehalose
Purity:	≥98% (HPLC)
Molecular Weight:	753.75

View Full Technical Details for 6 TMR Tre

Technical Data
Citations

Biological Activity for 6 TMR Tre

6 TMR Tre is a fluorescent trehalose conjugate for imaging bacterial cell envelope. Selectively labels mycobacterial trehalose monomycolate (TMM). Allows real-time visualization of peptidoglycan and monomycolate dynamics at the single-cell level. Suitable for use with confocal and super-resolution microscopy.

Optical Data for 6 TMR Tre

Emission Color	Yellow
λ_abs	532 nm
λ_em	580 nm

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Technical Data for 6 TMR Tre

M. Wt	753.75
Formula	C₃₇H₄₃N₃O₁₄
Storage	Store at -20°C
Purity	≥98% (HPLC)
Smiles	[H][C@]1([C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CNC(C3=CC(C([O-])=O)=C(C4=C(C=C/5)C(OC6=C4C=CC(N(C)C)=C6)=CC5=[N+](C)/C)C=C3)=O)O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 6 TMR Tre

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	5

Preparing Stock Solutions for 6 TMR Tre

The following data is based on the product molecular weight 753.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.07 mM	18.95 mL	94.76 mL	189.53 mL
0.35 mM	3.79 mL	18.95 mL	37.91 mL
0.7 mM	1.90 mL	9.48 mL	18.95 mL
3.5 mM	0.38 mL	1.90 mL	3.79 mL

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References for 6 TMR Tre

References are publications that support the biological activity of the product.

Rodriguez-Rivera Acute modulation of mycobacterial cell envelope biogenesis by front-line tuberculosis drugs. Angew.Chem.Int.Ed. 2018 PMID: 29392891