Phen Green SK diacetate

Name: Phen Green SK diacetate
Brand: Tocris Bioscience
SKU: 7873

Tocris Bioscience, part of Bio-Techne | Catalog # 7873

COA / SDS

Heavy metal ion indicator, membrane permeable

Key Product Details

Description:	Heavy metal ion indicator, membrane permeable
Chemical Name:	3',6'-Bis(acetyloxy)-2',7'-dichloro-3-oxo-N-1,10-phenanthrolin-5-yl-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide
Purity:	≥90% (HPLC)
Molecular Weight:	706.49

View Full Technical Details for Phen Green SK diacetate

Technical Data
Citations

Biological Activity for Phen Green SK diacetate

Phen Green SK diacetate is a fluorescent heavy metal ion indicator that can be used to detect various metal ions including Cu²⁺, Cu⁺, Fe²⁺, Hg²⁺, Pb²⁺, Cd²⁺, Zn²⁺ and Ni²⁺. Excitation and emission maxima (λ) are 507 and 532 nm, respectively. Intracellular Phen Green SK diacetate fluorescence is quenched upon reaction with metal ions. This product is cell permeable.

It is recommended to prepare stock solutions in DMSO.

Optical Data for Phen Green SK diacetate

λ_abs	507 nm
λ_em	532 nm
Extinction Coefficient (ε)	40000 M^-1cm^-1
Cell Permeable	Yes
Application	Fluorescence Microscopy, Flow Cytometry

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Technical Data for Phen Green SK diacetate

M. Wt	706.49
Formula	C₃₇H₂₁Cl₂N₃O₈
Storage	Store at -20°C
Purity	≥90% (HPLC)
CAS Number	234075-45-7
PubChem ID	137700453
InChi Key	INOXUAMBIQQWOK-UHFFFAOYSA-N
Smiles	O=C1OC2(C3=CC=C(C(NC4=CC5=CC=CN=C5C6=C4C=CC=N6)=O)C=C13)C7=CC(Cl)=C(C=C7OC8=CC(OC(C)=O)=C(C=C82)Cl)OC(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Phen Green SK diacetate

References are publications that support the biological activity of the product.

Kim Calibration of Phen Green for use as a Cu(I)-selective fluorescent indicator. Anal.Chim.Acta 2006 PMID: 17723595
Lu Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma. J.Exp.Clin.Cancer Res. 2022 PMID: 34980204
Shen Geniposide possesses the protective effect on myocardial injury by inhibiting oxidative stress and ferroptosis via activation of the Grsf1/GPx4 Axis. Front.Pharmacol. 2022 PMID: 35600863