QM-FN-SO3
Tocris Bioscience, part of Bio-Techne | Catalog # 7958
Key Product Details
| Description: | Blood-brain barrier penetrant, NIR aggregation-induced emission active probe of amyloid β plaques. Used for: in vitro, in situ and in vivo imaging of amyloid β plaques. Application: confocal microscopy and in vivo imaging |
| Chemical Name: | Sodium 3-(4-(Dicyanomethylene)-2-(2-(5-(4-(dimethylamino)phenyl)thiophen-2-yl)vinyl)quinolin-1(4H)-yl)propane-1-sulfonate |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 564.65 |
Biological Activity for QM-FN-SO3
Key information: QM-FN-SO3 is a near-infrared (NIR) aggregation-induced emission active probe for in vivo imaging of amyloid β (Aβ) plaques. Blood brain barrier penetrant.
Used for: detection of Aβ plaques in vitro, in situ and in vivo.
Application: confocal microscopy and in vivo imaging.
Properties and Photophysical Data: QM-FN-SO3 shows high binding affinity, ultra-high sensitivity, low signal-to-noise ratio, and large stokes shift (170 nm) reducing excitation light-induced self-quenching. Excitation and emission maxima (λ) are 488 nm and 680 nm, respectively.
Optical Data for QM-FN-SO3
| λabs | 488 nm |
|---|---|
| λem | 680 nm |
| Cell Permeable | Yes |
| Application | Confocal imaging of amyloid-beta plaques, in vitro and in vivo |
Plan Your Experiments
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